Abstracts by Dr. John Stehlin, as of 5/2/2001

20. Verschraegen CF, Mendoza J, Plaschke S, Melichar B,

Loercher A, Freedman R, Kudelka A, Kavanagh J, Stehlin JS and Giovanella BC. Rate of take of human ovarian cancer cells in vitro in tissue culture and in vivo in nude mice. 88th Annual AACR Meeting, San Diego, CA. April, 1997.

19. Giovanella BC, Pantazis P, Cao Z, Vardeman D, Mendoza J and Stehlin JS. Anticancer activity of stabilized camptothecins in vitro and in vivo. 88th Annual AACR Meeting, San Diego, CA. April, 1997.

18. Milan P, Vardeman D, Kozielski AJ, Mendoza J, Stehlin JS and Giovanella BC. Growth inhibition of human cancer metastases by camptothecins in newly-developed xenograft models. Proc Am Assoc Cancer Res 55:5637, 1995.

17. Potmesil M, Liebes L, Drygas J, Sekiya S, Morse L, Kozielski AJ, Wall ME, Wani MC, Stehlin JS and Giovanella BC. Pharmacodynamics/pharmacokinetics of intragastric (IG) camptothecin analogs in a human cancer xenograft model. Proc Am Assoc Cancer Res 36:445(2652), 1995.

16. Giovanella BC, Vardeman D, Kozielski AJ, Stehlin JS and Potmesil M. Enhanced antitumor effectiveness of camptothecin (CPT) and derivatives administered by continuous infusion through scheduling and combination with DNA damaging agents. Proc Am Assoc Cancer Res 36:391(2328), 1995.

15. Giovanella BC, Stehlin JS, Hinz HR, Vardeman D, Mendoza JT and Potmesil M. Studies of time/dose intensity in treatment of human cancer xenografts with camptothecin analogues. Proc Am Assoc Cancer Res 35:455(2713), 1994.

14. Giovanella BC, Potmesil M, Wall ME, Stehlin JS, Hinz HR, Vardeman D and Mendoza JT. Treatment of human cancer xenografts with camptothecin analogues in combination with cytoxan or x-irradiation. Proc Am Assoc Cancer Res 35:454(2711), 1994.

13. Giovanella BC, Wall ME, Wani MC, Stehlin JS, Hinz HR, Vardeman D, Mendoza JT, Kozielski AJ and Potmesil M. 10,11-Methylenedioxy camptothecins: studies in human cancer xenografts. Proc Am Assoc Cancer Res 34:327(1947), 1993.

12. Giovanella BC, Wall ME, Wani MC, Silber R, Stehlin JS, Hochster H and Potmesil M. Efficacy of camptothecin [NSC 94600], 9-aminocamptothecin [NSC 606174] in the human cancer xenograft model. Proc Am Assoc Cancer Res 33:507(2583), 1992.

11. Potmesil M, Hinz HR, Marcee A, Vardeman D, Stehlin JS, Wall ME, Wani MC, Silber R and Giovanella BC. Growth inhibition of human cancer metastases in the xenograft model by camptothecin (NSK 94600, 9-amino-[NSC 603071] and 9-nitrocamptothecin. Proc Am Assoc Cancer Res 33:507(2582), 1992.

10. Smith PL, Liehr JG, Ahmed AE, Hinz HR, Mendoza J, Kozielski A, Stehlin JS and Giovanella BC. Pharmacokinetics of tritium labeled camptothecin in nude mice. Proc Am Assoc Cancer Res 33:(507 2579), 1992.

9. Pantazis P, Hinz HR, Tschen J, Stehlin JS and Giovanella BC. Specific responses of human melanoma cells to treatment with camptothecin-derivatives in vitro. Proc Am Assoc Cancer Res 32:383 (2278), 1991.

8. Potmesil M, Wall ME, Wani MC, Silber R, Stehlin JS and Giovanella BC. 9-Amino [NSC 629971, 9-AC] and 10,11-methylenedioxy [NSC 6061764, 10,11-MDC] camptothecins in the treatment of human cancer xenografts. Proc Am Assoc Cancer Res 32:337 (2003), 1991.

7. Giovanella BC, Stehlin JS, Vardeman DM, Silber R and Potmesil M. DNA topoisomerase I-targeted treatment of liver and brainstem metastases in xenografts. Proc Am Assoc Cancer Res 32:337 (1999), 1991.

6. Giovanella BC, Vardeman DM and Stehlin JS. Further studies on rapid screening of anticancer agents by 111in-labeled human cancer cells inoculated in nude mice. Proc Am Assoc Cancer Res 29:493 (1961), 1988.

5. Verschraegen CF, Giovanella BC, Kozielski T, Mendoza JT and Stehlin JS. Increased sensitivity to cyclophosphamide (Cy) of artificial metastases of a human melanoma clone in nude mice. Proc Am Assoc Cancer Res 29:61(244), 1988.

4. Giovanella BC, Natelson EA, Kozielski T and Stehlin JS. Allogenic bone marrow transplantation in nude mice after lethal doses of cyclophosphamide. Proc Am Assoc Cancer Res 28:431(1707), 1987.

3. Giovanella BC, Verschraegen CF, Kozielski T and Stehlin JS. Distribution and fate of 111in-labeled human melanoma cells after intracardiac and intravenous injection in nude mice. Proc Am Assoc Cancer Res 28:75(299), 1987.

2. Verschraegen CF, Giovanella BC, Mendoza JT and Stehlin JS. Metastatic spread of human melanoma clones inoculated in the arterial and venous circulation of nude mice. Proc Am Assoc Cancer Res 28:75(298), 1987.

1. Lockshin A, Giovanella BC and Stehlin JS. Quantitative evaluation of anticancer agents against human melanoma cells implanted in nude Mice. Exp Cell Biol 54(3):149-54, 1986.